SAMe (S-Adenosylmethionine) 60 caps Pure Encapsulations

√ Functions as a donor of methyl groups in over 100 different reactions catalyzed by methyltransferase enzymes, as well as a precursor molecule for glutathione and polyamine synthesis

√ Supports positive mood and cognitive function

• In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood
• Promotes healthy protein turnover to support healthy CNS function
• Maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity
• Supports neurotransmitter monoamine synthesis and function, including dopamine and serotonin, through SAMe-dependent methylation reactions

√ Promotes liver function by supporting glutathione production

• Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells

√ Enhances joint comfort by supporting proteoglycan synthesis, as well as helping to stabilize and protect proteoglycans

• In a 16-week randomized, double-blind, placebo-controlled trial involving 56 subjects, SAMe offered statistically significant support for joint comfort

√ Maintains healthy cell growth and cytokine balance by supporting healthy polyamine production